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Allulose Membrane Separation and Purification Process

Allulose Membrane Separation and Purification Process

Efficient Ultrafiltration and Nanofiltration Combination Technology, Enhancing Allulose Purity and Recovery Rate

Introduction

Amid the continuous rise in global obesity rates, developing natural and healthy rare sugars as alternatives to traditional sweeteners has become a research hotspot. D-Allulose, with its low calorie content (approximately 0.3% of sucrose), high sweetness (about 70% of sucrose), and various biological activities (such as blood sugar reduction, weight control, and antioxidation), has garnered significant attention and has received safety certification from the U.S. FDA. Utilizing D-allulose 3-epimerase (DPE) to isomerize D-fructose is currently the most economical and environmentally friendly production method, requiring multiple purification steps such as decolorization and ion exchange to obtain high-quality products. To improve separation efficiency and purity, Plum Membrane Technology Co., Ltd. employs an "ultrafiltration + nanofiltration" membrane separation process, efficiently removing proteins, pigments, and polysaccharide impurities, simplifying the workflow, enhancing recovery rates, and meeting the demands for industrialized continuous production.

Background & Challenges


Allulose isomerization liquid contains impurities such as proteins, polysaccharides, and disaccharides, affecting chromatographic and crystallization stability
Conventional ion exchange and evaporation impose heavy loads, with high sugar loss and energy consumption
Thermally sensitive sugars require mild processing to avoid degradation
Multiple process steps pose risks of cross-contamination and recycle material loops

Process Flow


 

The fermentation broth first undergoes allulose isomerization to convert part of the fructose into allulose, followed by decolorization to remove pigments and phenols, enhancing the liquid's purity and sensory quality. Next, ion exchange removes residual impurities and salts, and ultrafiltration membrane separation further eliminates high-molecular-weight impurities and colloids, ensuring stability in subsequent concentration and crystallization stages. After evaporation concentration to increase allulose content, part of the solution directly enters chromatographic refining, while another portion undergoes nanofiltration purification to further remove small-molecule impurities before entering evaporation crystallization, ultimately yielding high-purity allulose crystalline products that meet high-quality demands for food, health supplements, and functional ingredients.

Process Highlight


Specialized Membrane Combination and Continuous Separation Technology:Continuous ultrafiltration + nanofiltration combination replaces some conventional stages, reducing contamination risks and improving product quality consistency.
High Recovery Rate:Ultrafiltration achieves over 99% retention of sugar dry basis, while nanofiltration effectively removes polysaccharides, disaccharides, and small-molecule impurities, with an overall allulose recovery rate ≥85%.
Mild Processing and Stable Operation:The membrane system involves no phase changes and low shear, protecting thermally sensitive components, suitable for food-grade continuous operation.
Energy Saving, Emission Reduction, and Compact Process:Reduces the burden on activated carbon/ion exchange/evaporation systems, lowering energy consumption and operating costs, with a small footprint.

Applications


Industrial Preparation and Purification of Allulose
Membrane Separation of Functional Oligosaccharides and Rare Sugars
Upgrades to Post-Processing Systems for Fructose Isomerization Products
Optimization of Food-Grade Sugar Separation and Purification Processes

Case Photos


Allulose Ultrafiltration Separation Equipment

Allulose Ultrafiltration Separation Equipment

Allulose Ultrafiltration Separation Equipment

Allulose Ultrafiltration Separation Equipment

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Anhui Plum Membrane Technology Co., Ltd.

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